Epitalon Australia: Buy Epitalon Online

Shop Epitalon Peptide in 10 mg and 50 mg Vials With Lot Data

Name	Epitalon (epithalon, AEDG)
Sizes and prices (AUD)	10 mg vial at $45, 50 mg vial at $89
Sequence or structure	Ala-Glu-Asp-Gly, linear tetrapeptide with a free C-terminal acid
Length	4 amino acids
Molecular formula	C14H22N4O9
Molar mass	390.3 g/mol
CAS number	307297-39-8
Form	Lyophilised powder in a sealed glass vial with flip-off cap
Testing	Identity by mass spectrometry, purity by HPLC, a certificate of analysis for every lot
Contents	One vial of Epitalon powder per unit (10 mg or 50 mg), supplied without diluent, with bacteriostatic water sold separately
Storage	Sealed vial at -20 °C, dry and protected from light. In solution at 2 to 8 °C
Availability	In stock
Use	Laboratory in vitro research only

Order Epitalon for cell ageing programmes with a clear choice of fill, the 10 mg vial for a pilot or the 50 mg vial for long culture series at a far lower cost per milligram. Both sizes are in stock in Australia, and each batch carries its own certificate.

What Is Epitalon?

Epitalon is a lab-made peptide only four amino acids long, studied as a possible switch for telomerase, the enzyme that rebuilds the protective caps on the ends of chromosomes. Epitalon peptide belongs to a family the Russian literature calls bioregulators: very short chains of two to four residues that are proposed to act on gene expression rather than on a classic receptor at the cell surface.

How Epitalon works in research models

Each time a typical human cell divides, its telomeres (stretches of the repeat TTAGGG at every chromosome tip) get a little shorter. Telomerase can add those repeats back, but in most adult somatic cells the gene for its catalytic subunit, hTERT, is barely active, so the caps wear down until the cell stops dividing. The working idea behind AEDG is that it nudges hTERT expression upward. How a molecule this small would manage that is not settled. The founding group argues that short peptides reach the nucleus and bind specific DNA sequences in promoter regions, a hypothesis resting mostly on molecular modelling and their own cell data rather than an accepted mechanism.

The strongest outside support arrived in 2025, when a team at Brunel University London reported in Biogerontology that the peptide lengthened telomeres in normal human mammary epithelial cells and IBR.3 fibroblasts, in a dose-dependent way, through telomerase upregulation. Those cells were exposed for three weeks at 0.1 to 1 µg/mL. In the breast cancer lines 21NT and BT474 the extension ran through a different route, alternative lengthening of telomeres (ALT), and the journal later printed a correction replacing three of the figures.

Animal data come mainly from Vladimir Anisimov's group at the Petrov Institute of Oncology. In their 2003 study of female SHR mice, 54 per group, treated animals showed no change in mean lifespan, body weight or overall tumour incidence. Yet the longest-lived 10 per cent survived 13.3 per cent longer, maximum lifespan rose 12.3 per cent, leukaemia was six times less common and chromosome aberrations in bone marrow fell by 17.1 per cent.

Our practical read: that mouse paper is the one most often misquoted. Its result is a longer tail of survivors, not a longer average life. A lab planning an ageing study should decide up front whether the endpoint is telomere length, hTERT transcript levels or survival, because the cell work has given clearer answers on the first two. For telomere length assays such as qPCR or TRF blots, budget at least three weeks of exposure, since that is how long the Brunel cultures ran before the change was measured.

Is Epitalon Legal in Australia? The Vial, Its Origins and Its Status

What is Epitalon once it is on the bench? A sealed glass vial holding a small white lyophilised cake, either 10 mg or 50 mg of the AEDG tetrapeptide, supplied dry so the lab chooses its own diluent. The sequence traces back to epithalamin, a polypeptide preparation of bovine pineal gland that Khavinson's group studied at the Kirov Military Medical Academy in Leningrad from the early 1980s. Khavinson went on to found the St Petersburg Institute of Bioregulation and Gerontology in 1992, and the four-residue synthetic followed as a way to study one defined molecule instead of a variable gland extract. That single, characterised structure is the reason a certificate for each lot means something.

Epitalon in Australia has no medicines pathway behind it. As of October 2026 the compound is not named anywhere in the Poisons Standard (we checked the October 2026 instrument), so it carries no schedule. Unscheduled does not mean approved, though. The TGA treats a peptide supplied for therapeutic purposes without an entry on the Australian Register of Therapeutic Goods as an unapproved product, and it has made unapproved peptides a compliance priority. In practice that leaves the research market as the usual source, which is why searches for Epitalon peptide Australia turn up reagent suppliers rather than clinics or dispensaries.

Buy Epitalon Australia stock from AminoBlend and both fills come from inventory held locally, sold as a research reagent for laboratory use to adults 18 and over, never for human or veterinary use. Labs comparing the Khavinson peptides often pair it with Thymalin, the thymic bioregulator from the same programme, and our research use policy sets out the terms every order is accepted under.

Buy Epitalon Peptide Online in Australia for Telomerase and Pineal Research

Buy Epitalon and you are choosing the most documented of the short bioregulators from Vladimir Khavinson's school at the St Petersburg Institute of Bioregulation and Gerontology. In the 1980s that team worked with epithalamin, a crude polypeptide extract of bovine pineal gland, and later synthesised the four-residue sequence Ala-Glu-Asp-Gly to reproduce part of its activity in a single, defined molecule. A widely cited 2003 paper reported telomerase activation and telomere elongation in cultured human fibroblasts, and that report still frames the central question of whether a peptide this small can shift gene expression tied to cellular ageing.

Later work from the same group looked at night-time melatonin rhythms in aged rodents and primates and at lifespan markers in rodents and fruit flies, while a newer hypothesis proposes that very short peptides interact with chromatin. Replication outside the founding group is still limited, which is exactly why lot-tested material matters. Shop it within our longevity peptides range, next to the other sequences from the Khavinson programme, as a research reagent with no connection to any medicine.

Order Epitalon for Skin Cell and Fibroblast Research

Interest in Epitalon peptide benefits for skin comes from in vitro work, not from anything applied to people. The fibroblast telomerase data, together with follow-up studies on dermal cell senescence markers and collagen-related gene expression, made AEDG a reference tetrapeptide for labs that culture skin-derived cells. Order it for that kind of bench work, where a defined four-residue sequence can be tested against passage number, senescence staining or matrix gene panels.

Order Epitalon for Sale in Two Fills With Lot Tracking and One Certificate

Order the 10 mg vial at $45 for solubility checks, a first concentration series in a new cell line or a short pilot. The 50 mg vial at $89 drops the cost from $4.50 to about $1.78 per milligram and keeps a long telomerase or senescence study on one batch of material. Both fills are made to the same specification, so moving between them mid-project does not change the compound under test.

Buy several vials in one go and they ship from a single lot wherever stock allows under one certificate, which keeps the lab notebook tidy when results are compared months later. Epitalon is sold only to buyers aged 18 and over, confirmed at checkout.

Buy Epitalon With Structure, Purity and Lot Certificate Confirmed

AEDG is small and very polar. Two acidic residues, glutamate and aspartate, sit between an N-terminal alanine and a C-terminal glycine, so the powder dissolves readily in water-based diluents. It carries no protecting groups, which separates it from N-acetyl epitalon amidate, a capped analogue with a heavier mass that we do not stock.

Shop with the certificate in hand and look for a measured mass that agrees with 390.3 g/mol and an HPLC trace dominated by one main peak, with the purity figure reported for that specific lot. Each certificate is published in the COA library under the lot number printed on the vial label, so the document you file belongs to your powder.

Order Epitalon Online for Delivery Near You and Store the Vial

AminoBlend has no shopfront or pickup counter. The store runs entirely online and serves every state and territory from stock held in Australia. Labs sourcing research peptides in Melbourne order from the same certified lots as everyone else, with orders paid before 3pm on a business day dispatched the same afternoon, and delivery information lists the timings.

The vial holds powder only. Let it reach room temperature, run the diluent slowly down the inside wall of the glass and swirl gently rather than shaking. Adding 2 mL of bacteriostatic water to the 10 mg vial gives 5 mg/mL, and 10 mL in the 50 mg vial gives the same strength, while the peptide calculator handles any other volume.

Sealed, the vial keeps at -20 °C, dry and dark, and the dry cake tolerates a short spell at room temperature in transit. Once dissolved, store the solution at 2 to 8 °C, divided into aliquots so each portion is thawed only once.

Other Names for Epitalon

Epitalon and epithalon are two transliterations of the same Russian name, and both describe the tetrapeptide sold here. Papers also use AEDG, its one-letter code, and the full chemical name L-alanyl-L-glutamyl-L-aspartyl-glycine. Older articles call it the synthetic analogue of epithalamin, sometimes written epitalamin, the pineal extract it was designed to replace. Whatever the label, the identity markers stay fixed at CAS 307297-39-8 and the formula C14H22N4O9.

Order Epitalon or Pinealon, or Build a Bioregulator Panel

Both are Khavinson bioregulators, yet they answer different questions. Epitalon, at four residues, is studied mostly in telomerase, pineal and fibroblast ageing models. Pinealon, the tripeptide Glu-Asp-Arg, turns up mainly in neuronal culture work on oxidative stress. Pick Epitalon for ageing markers in dividing cells, Pinealon for neuronal endpoints, or both when one study needs two peptides from the same school.

Shop Cartalax for a tighter structural control, since it is AEDG without its final glycine. For pineal rhythm and sleep research, the trio labs most often group together is DSIP, Epitalon and Pinealon, so DSIP is worth adding when melatonin timing is part of the design.