SS-31 Australia: Buy SS-31 Elamipretide Online

Shop SS-31 Peptide 10 mg With Lot Data and Chemical Identity

Order this vial when a project calls for a small, cell-permeant tool that works inside the inner mitochondrial membrane instead of acting on a surface receptor. Each 10 mg lot sits in Australian stock and is released only after it clears HPLC and mass checks.

What Is SS-31?

SS-31 is a four-residue synthetic peptide that concentrates inside mitochondria and sticks to cardiolipin, a fat found almost nowhere else, which is why researchers use it as a tool for studying how mitochondrial membranes fail. The SS in the name is simply Szeto-Schiller, after its two designers, and 31 is its number in their compound series.

Cardiolipin is the detail that makes the compound worth explaining. Unlike ordinary phospholipids with two fatty tails, cardiolipin carries four, and it sits almost exclusively in the folded inner mitochondrial membrane where energy production happens. Those folds, the cristae, depend on it to curve properly, and the respiratory complexes that pass electrons along the chain are held in place by it. Cytochrome c binds cardiolipin too, which matters because the bound form can switch jobs: instead of ferrying electrons, it begins attacking the lipid itself, oxidising the very molecule holding the machinery together. Once that starts, cristae flatten out and the membrane leaks.

How SS-31 is thought to work in research models

Work from Hazel Szeto's group, with Alexander Birk as first author in the Journal of the American Society of Nephrology in 2013, reported that a fluorescent version of the peptide bound cardiolipin tightly, and that the resulting complex blocked the peroxidase activity of cytochrome c by shielding its haem iron while leaving its electron-carrying role intact. In a kidney ischaemia model, treatment preserved cristae structure. The chemistry traces back to the group's earlier opioid-analogue work, where a related tetrapeptide numbered SS-02 was found to collect in mitochondria, and the series was rearranged to keep that targeting.

Two practical points, since this is the compound labs most often misuse. First, it is not an antioxidant in the usual sense and will disappoint anyone screening it as a radical scavenger. Its reported action is structural, keeping one lipid and one protein locked in a particular arrangement, so the readouts that show anything are cristae morphology by electron microscopy, respiratory control ratios in isolated mitochondria, or the ratio of oxidised to intact cardiolipin by lipidomics. Second, the molecule is strongly cationic, so at low concentrations a real share of it will bind glass and ordinary plastics before it ever reaches a cell. Prepare dilutions in low-binding labware and make them fresh, or your stated concentration and your actual one will part company.

Buy SS-31 Peptide Online in Australia for Mitochondrial Membrane Research

Hazel Szeto and Peter Schiller designed the Szeto-Schiller series in the early 2000s, beginning with opioid peptide chemistry and arriving at molecules aimed at mitochondria. SS-31 alternates positive charges with aromatic rings and holds a net charge of +3 at physiological pH, yet it still crosses into cells and gathers in the inner membrane without relying on membrane potential. Buy it for work on depolarised or damaged mitochondria, where probes driven by potential lose their grip.

The question it helps answer is narrow and practical. What happens to electron transport and reactive oxygen species output when cardiolipin, the phospholipid anchoring the respiratory complexes, is protected from peroxidation? Elamipretide has also passed through clinical development, but the powder sold here is a research reagent with no tie to any medicine. Shop the wider mitochondrial peptides range for related tools.

SS-31 and Elamipretide in Australia: An Approved Drug Overseas, a Reagent Here

The vial is a 3 mL glass vial with an amber flip-off cap and a white label, holding 10 mg of white lyophilised SS-31 and nothing else. Because the tetrapeptide weighs only 639.8 g/mol, a milligram of it holds about 3.4 times as many molecules as a milligram of MOTS-c. The chemistry came from a collaboration between Hazel Szeto at Weill Cornell Medical College in New York and Peter Schiller at the Clinical Research Institute of Montreal, and Stealth BioTherapeutics later took the compound into clinical trials under the name elamipretide.

The status of elamipretide changed in 2025. On 19 September 2025 the US FDA granted accelerated approval to Forzinity (elamipretide) as the first treatment for Barth syndrome, a rare inherited disorder of cardiolipin metabolism, with a confirmatory trial required as a condition of that approval. Registry entries for its confirmatory trial state that the product has not been approved outside the United States, and we found no ARTG entry for it as of October 2026, so there is no registered elamipretide medicine in Australia. That confirmatory study names Australia among the countries outside the US where it planned to enrol.

Buying SS-31 in Australia as a Research Peptide

The FDA decision has not changed what this page sells. SS-31 for sale in Australia from AminoBlend is a research-grade peptide, not Forzinity, not made by Stealth and not assessed by the TGA. We hold the 10 mg vial in Australian stock, available to order online by adults 18 and over, for laboratory research only and never for human or veterinary use. Labs that buy SS-31 in Australia for membrane work often pair it with a 500 mg NAD+ vial to cover the cofactor side of the same redox question.

Order SS-31 for Sale in One 10 mg Format With Lot Tracking

SS-31 is stocked as a single 10 mg fill at $99, which buys exactly ten milligrams of a non-natural tetrapeptide with three modified positions. At 639.8 g/mol that quantity equals roughly 15.6 micromoles, enough for assay development in isolated mitochondria, several cell culture plates or a short ischaemia series run by one team.

Order every vial a multi-week project needs at the outset. Multi-vial orders are picked from one lot wherever stock allows, so the full study sits under a single certificate and batch variation drops out of the comparison. Checkout asks buyers to confirm they are 18 or older, and the product is sold for laboratory research only.

Buy SS-31 in Stock With a Published Purity and Lot Certificate

Three features make this molecule harder to build than its length suggests. A D-arginine at the N-terminus shields it from aminopeptidases, a non-natural 2',6'-dimethyltyrosine sits in second position, and the C-terminal phenylalanine is amidated. A product missing any of them can still look like white powder, so identity is confirmed by mass and never by appearance.

Read the certificate for a measured mass consistent with 639.8 g/mol, the HPLC purity result for that lot, the analysis date and the lot code printed on your label. Every report is filed in the COA library, open to read before the vial goes into your cart.

Order SS-31 Near You Online and Store the Powder Correctly

AminoBlend runs no shopfront or pickup counter. The store works entirely online and serves every state and territory from stock held in Australia, with same-day dispatch for orders placed before 3pm on a business day. Timeframes are set out on the delivery information page.

To reconstitute, let the sealed vial reach room temperature, guide the diluent slowly down the inside of the glass and swirl instead of shaking. Small and highly charged, SS-31 dissolves readily, and 2 mL of bacteriostatic water gives 5 mg/mL, or 0.5 mg in each 0.1 mL. Use the reconstitution calculator for any other volume.

Hold the sealed vial at -20 °C away from light. After mixing, move the solution to 2 to 8 °C, split it into aliquots so the stock vial is not pierced again and again, and finish it within 28 days. Cationic peptides can stick to some plastics, so low-binding tubes keep the concentration where you set it. The peptide storage guide goes further into shelf life.

Other Names for SS-31 and Elamipretide

The same tetrapeptide is sold and published as SS-31, SS31 without the hyphen, elamipretide (its non-proprietary name), MTP-131 and Bendavia, an earlier development name. Chemistry papers may spell it out as D-Arg-2',6'-Dmt-Lys-Phe-NH2 or call it a Szeto-Schiller peptide. Every label leads back to one structure registered under CAS 736992-21-5.

Its mechanism carries its own vocabulary, including cardiolipin, inner mitochondrial membrane, electron transport chain, cytochrome c peroxidase activity and mitochondria-targeted antioxidant peptide. These terms describe the research setting rather than separate products.

Order SS-31 or MOTS-c Depending on Your Research Question

Pick SS-31 when the question concerns the membrane itself, such as cardiolipin integrity, respiratory complex efficiency or oxidant leak in isolated mitochondria. Pick MOTS-c when the question concerns signalling, since that 16 amino acid peptide is encoded in mitochondrial DNA and acts through AMPK and nuclear gene expression.

Shop all three if your redox design also needs NAD+, a coenzyme rather than a peptide, to cover the metabolic side. Each vial carries its own lot certificate, and they can share one order. For senescence or whole-cell ageing work, the longevity peptides range lists further tools.