CJC 1295 With DAC Australia: Buy CJC-1295 DAC Online

Shop CJC 1295 with DAC 5 mg With Full Lot Data and Chemical Identity

Order CJC-1295 With DAC when a study needs the GHRH receptor held under stimulation for days rather than minutes. Each 5 mg vial is packed in Australia with its own HPLC report, and the DAC versus No DAC section further down helps settle the choice before you reach the cart.

What Is CJC 1295 DAC?

CJC-1295 DAC is a stabilised fragment of growth hormone releasing hormone fitted with a small chemical hook that latches onto albumin, the main protein in blood plasma, so it keeps signalling for days instead of minutes. The hook is the drug affinity complex, or DAC. Strip it away and what remains is the same receptor-binding chain sold as the No DAC form.

What the DAC does, in plain chemistry

The reactive end of the hook is a maleimide ring. Maleimides react quickly and selectively with thiol groups, the sulphur-hydrogen pairs found on cysteine, and form a stable thioether bond. Human serum albumin has 35 cysteines, but 34 of them are locked into disulfide bridges, which leaves a single free thiol at position 34 as the obvious partner. Albumin is abundant, at roughly 35 to 50 grams per litre of plasma, and a recycling receptor rescues it from breakdown, giving it a half-life of about three weeks, so anything bolted to it inherits a long life. In effect, the peptide borrows albumin's lifespan.

The idea was tested before any human study. In a 2005 Endocrinology paper, Jetté and colleagues attached maleimide derivatives of GRF 1-29 to human albumin outside the body, showed the conjugates resisted DPP-4 and still triggered growth hormone secretion from cultured rat pituitary cells, and named CJC-1295 as the long-lasting lead. Work in GHRH knockout mice by Alba and colleagues the following year then asked whether this conjugate could stand in for the missing hormone over weeks of treatment.

The receptor it reaches is unchanged. CJC 1295 with DAC binds the GHRH receptor on somatotrophs exactly as the short form does. What changes is the exposure: instead of brief spikes, the receptor sees a steady presence, which lifts the floor of growth hormone release while the natural pulses carry on above it.

Here is the point we see missed most often. The long half-life is a property of plasma, not of the vial. In serum-free culture medium there is no albumin to bind, so the conjugate behaves much like a short GHRH analogue. In medium with fetal bovine serum, the maleimide grabs bovine albumin instead, which also carries a free cysteine. And thiol reagents such as DTT, 2-mercaptoethanol or excess free cysteine will consume the maleimide before it ever meets a protein, so keep them out of any buffer used to prepare it. The full half-life comparison of both CJC-1295 forms covers how each one fits a sampling schedule.

Buy CJC 1295 with DAC Online in Australia, the Albumin-Bound GHRH Analogue

Buy the original long-acting form of Mod GRF (1-29) from a local supplier that documents every lot. The drug affinity complex was developed in the early 2000s by ConjuChem, a Montreal biotechnology company, to keep short peptides in circulation for longer. Applied to a stabilised GHRH fragment, it produced CJC-1295 With DAC. Once the maleimide group meets albumin, it forms a covalent bond with the free cysteine at position 34, and the peptide then travels on that carrier protein. Pharmacokinetic papers from 2005 and 2006, including the Teichman study, reported a half-life of roughly six to eight days, against a few minutes for native GHRH.

That sets up a precise laboratory question. What happens when the GHRH receptor on pituitary somatotrophs, a Gs-coupled receptor signalling through cAMP, is stimulated continuously instead of in pulses? Shop the vial as a research reagent, never a medicine, alongside the other secretagogues in our growth hormone peptides range.

Buying CJC 1295 DAC in Australia: What You Receive and Its Legal Position

The order is one 5 mg vial under a purple flip-off cap, the conjugate dried to a white powder with no diluent, carrier or companion peptide in the glass. Half the fill of the No DAC vial is deliberate, for reasons set out further down this page. What sits inside began as a clinical candidate. ConjuChem enrolled 192 participants with HIV-associated visceral obesity in a placebo-controlled phase 2 trial, then stopped it in July 2006 after a participant died at a site in Argentina; the attending physician linked the death to coronary artery disease rather than the drug, but the programme never resumed and no product reached the market.

That history explains the regulatory picture. Australian law names this molecule precisely: the Poisons Standard entry "CJC-1295 (CAS No. 863288-34-0)" uses the same CAS number printed on our certificates. As of October 2026, under the June 2026 instrument, that entry sits in Schedule 4 as a prescription-only medicine and in Appendix D, clause 5, which makes possession without authority illegal. The listing dates from the TGA's 2014 to 2015 review of growth hormone releasing peptides and related compounds, yet there is still no registered product on the ARTG for a prescriber to choose, which is why CJC-1295 DAC in Australia is met almost exclusively as a research chemical.

WADA names CJC-1295 among the GHRH analogues in class S2 of its 2026 Prohibited List, and Sport Integrity Australia tests against that list, and the ban applies in and out of competition.

We hold CJC-1295 With DAC in Australian stock as a laboratory reagent for adults aged 18 and over, supplied for in vitro research only and not for human or veterinary use. Labs that want the No DAC core as well can order the CJC-1295 and ipamorelin blend for paired designs.

Order the 5 mg CJC-1295 DAC Vial for Sale With Lot Tracking

Order CJC-1295 With DAC in one 5 mg fill at $79, which works out at $15.80 per mg. The small fill follows from the long half-life, since a compound that stays bound to albumin for days needs far less material across a study series than a short-acting analogue. The extra coupling step in synthesis, attaching and purifying the maleimide linker, also explains why each milligram costs more than the No DAC core.

Buy several vials in one checkout and they arrive from a single lot wherever stock allows, so a whole series sits under one certificate number. That matters for long projects, where switching lots halfway through adds a variable nobody planned for. Sales are limited to buyers aged 18 and over, who confirm their age and accept the research use policy before payment.

Buy CJC-1295 With DAC From Stock With a Verified Structure and Certificate

The core is Mod GRF (1-29), the first 29 residues of human GHRH with four enzyme-resistant substitutions, namely D-alanine at position 2, glutamine at 8, alanine at 15 and leucine at 27. A C-terminal lysine then carries the maleimidopropionyl group. That addition brings the conjugate to 3647.2 g/mol, about 280 g/mol heavier than the 3367.9 g/mol No DAC peptide, and the gap is the quickest way to tell two identical white powders apart.

Check three things on the certificate before any repeat order. Look for a measured mass matching the DAC molecule, the CAS 863288-34-0 and an HPLC purity figure for the lot number printed on the vial. Every report is filed in the COA library, and the guide to reading a certificate of analysis explains each line.

Order CJC 1295 with DAC Near You, Then Store the Vial Cold

Order from anywhere in the country, because AminoBlend has no shopfront or pickup counter and serves every state and territory from one Australian stock. Labs sourcing research peptides in Canberra check out through this page like everyone else. Orders paid before 3pm on a business day leave that afternoon, and the vial, the lot and the certificate are the same wherever your lab is based.

The maleimide group can slowly hydrolyse in water, particularly at higher pH, so reconstitute only when the work is ready to begin. Let the vial reach room temperature, run bacteriostatic water down the glass wall and swirl gently without shaking. Adding 2 mL to the 5 mg vial gives 2.5 mg/mL. The peptide calculator handles any other volume, and the reconstitution guide covers aseptic technique.

Sealed powder keeps best at -20 °C in its carton, away from light and moisture. Once dissolved, the solution belongs at 2 to 8 °C and should be used within 28 days, ideally split into single-use aliquots so the stock is not warmed again and again.

Other Names for CJC-1295 With DAC

Supplier catalogues list this compound as CJC-1295 DAC, long-acting CJC-1295 or simply DAC CJC. Older literature describes it as a GRF (1-29) analogue conjugated to a drug affinity complex, or as an albumin-binding GHRH analogue. Each label points to the same 29 residue core with its lysine-linked maleimide, registered under CAS 863288-34-0.

The receptor vocabulary helps too. GHRH stands for growth hormone releasing hormone, sometimes written GRF or somatocrinin, and its receptor is abbreviated GHRHR. The downstream marker most studies track is IGF-1, insulin-like growth factor 1, which the liver produces in response to growth hormone.

CJC 1295 DAC or No DAC, Which One to Order

Both forms share the same Mod GRF core, and the only difference is the linker. With DAC, the molecule persists for days and suits sustained-elevation designs. Without it, CJC-1295 No DAC clears in about 30 minutes, sits closer to the natural pulse and sells as a 10 mg vial for $79. Order both to isolate the effect of albumin binding while the receptor-binding sequence stays constant.

Tesamorelin keeps the full 44 residue GHRH chain instead, and ipamorelin works through the ghrelin receptor rather than GHRHR. Our DAC versus No DAC comparison sets the two CJC-1295 forms side by side in more detail, including half-life, fill size and which designs each one fits.